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Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture

BACKGROUND AND PURPOSE: Hemiarthroplasty is the most common treatment in elderly patients with displaced femoral neck fracture. Prosthetic joint infection (PJI) is a feared complication. The infection rate varies in the literature, and there are limited descriptive data available. We investigated th...

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Autores principales: Guren, Ellen, Figved, Wender, Frihagen, Frede, Watne, Leiv Otto, Westberg, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Hip
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499328/
https://www.ncbi.nlm.nih.gov/pubmed/28271919
http://dx.doi.org/10.1080/17453674.2017.1301009
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author Guren, Ellen
Figved, Wender
Frihagen, Frede
Watne, Leiv Otto
Westberg, Marianne
author_facet Guren, Ellen
Figved, Wender
Frihagen, Frede
Watne, Leiv Otto
Westberg, Marianne
author_sort Guren, Ellen
collection PubMed
description BACKGROUND AND PURPOSE: Hemiarthroplasty is the most common treatment in elderly patients with displaced femoral neck fracture. Prosthetic joint infection (PJI) is a feared complication. The infection rate varies in the literature, and there are limited descriptive data available. We investigated the characteristics and outcome of PJI following hemiarthroplasty over a 15-year period. PATIENTS AND METHODS: Patients with PJI were identified among 519 patients treated with hemiarthroplasty for a femoral neck fracture at Oslo University Hospital between 1998 and 2012. We used prospectively registered data from previous studies, and recorded additional data from the patients’ charts when needed. RESULTS: Of the 519 patients, we identified 37 patients (6%) with early PJI. 20 of these 37 patients became free of infection. Soft tissue debridement and retention of implant was performed in 35 patients, 15 of whom became free of infection with an intact arthroplasty. The 1-year mortality rate was 15/37. We found an association between 1-year mortality and treatment failure (p = 0.001). Staphylococcus aureus and polymicrobial infection were the most common microbiological findings, each accounting for 14 of the 37 infections. Enterococcus spp. was found in 9 infections, 8 of which were polymicrobial. There was an association between polymicrobial infection and treatment failure, and between polymicrobial infection and 1-year mortality. INTERPRETATION: PJI following hemiarthroplasty due to femoral neck fracture is a devastating complication in the elderly. We found a high rate of polymicrobial PJIs frequently including Enterococcus spp, which is different from what is common in PJI after elective total hip arthroplasty.
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spelling pubmed-54993282017-08-01 Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture Guren, Ellen Figved, Wender Frihagen, Frede Watne, Leiv Otto Westberg, Marianne Acta Orthop Hip BACKGROUND AND PURPOSE: Hemiarthroplasty is the most common treatment in elderly patients with displaced femoral neck fracture. Prosthetic joint infection (PJI) is a feared complication. The infection rate varies in the literature, and there are limited descriptive data available. We investigated the characteristics and outcome of PJI following hemiarthroplasty over a 15-year period. PATIENTS AND METHODS: Patients with PJI were identified among 519 patients treated with hemiarthroplasty for a femoral neck fracture at Oslo University Hospital between 1998 and 2012. We used prospectively registered data from previous studies, and recorded additional data from the patients’ charts when needed. RESULTS: Of the 519 patients, we identified 37 patients (6%) with early PJI. 20 of these 37 patients became free of infection. Soft tissue debridement and retention of implant was performed in 35 patients, 15 of whom became free of infection with an intact arthroplasty. The 1-year mortality rate was 15/37. We found an association between 1-year mortality and treatment failure (p = 0.001). Staphylococcus aureus and polymicrobial infection were the most common microbiological findings, each accounting for 14 of the 37 infections. Enterococcus spp. was found in 9 infections, 8 of which were polymicrobial. There was an association between polymicrobial infection and treatment failure, and between polymicrobial infection and 1-year mortality. INTERPRETATION: PJI following hemiarthroplasty due to femoral neck fracture is a devastating complication in the elderly. We found a high rate of polymicrobial PJIs frequently including Enterococcus spp, which is different from what is common in PJI after elective total hip arthroplasty. Taylor & Francis 2017-08 2017-03-08 /pmc/articles/PMC5499328/ /pubmed/28271919 http://dx.doi.org/10.1080/17453674.2017.1301009 Text en © 2017 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation. https://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (https://creativecommons.org/licenses/by-nc/3.0)
spellingShingle Hip
Guren, Ellen
Figved, Wender
Frihagen, Frede
Watne, Leiv Otto
Westberg, Marianne
Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title_full Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title_fullStr Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title_full_unstemmed Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title_short Prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
title_sort prosthetic joint infection—a devastating complication of hemiarthroplasty for hip fracture
topic Hip
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499328/
https://www.ncbi.nlm.nih.gov/pubmed/28271919
http://dx.doi.org/10.1080/17453674.2017.1301009
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