Cargando…

Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli

New antibiotics are required to treat bacterial infections and counteract the emergence of antibiotic resistance. Pathogen-specific antibiotics have several advantages over broad-spectrum drugs, which include minimal perturbation to the commensal microbiota. We present a strategy for targeting antib...

Descripción completa

Detalles Bibliográficos
Autores principales: Chairatana, Phoom, Zheng, Tengfei, Nolan, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499518/
https://www.ncbi.nlm.nih.gov/pubmed/28717471
http://dx.doi.org/10.1039/c5sc00962f