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Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA–protein correlations at the level of single cells

The use of synthetic messenger ribonucleic acid (mRNA) to express specific proteins is a highly promising therapeutic and vaccine approach that avoids many safety issues associated with viral or DNA-based systems. However, in order to optimize mRNA designs and delivery, technology advancements are r...

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Detalles Bibliográficos
Autores principales:	Kirschman, Jonathan L., Bhosle, Sushma, Vanover, Daryll, Blanchard, Emmeline L., Loomis, Kristin H., Zurla, Chiara, Murray, Kathryn, Lam, Blaine C., Santangelo, Philip J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499550/ https://www.ncbi.nlm.nih.gov/pubmed/28449134 http://dx.doi.org/10.1093/nar/gkx290

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