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Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain
The editing function of aminoacyl-tRNA synthetases (aaRSs) is indispensible for formation of the correct aminoacyl-tRNAs. Editing deficiency may lead to growth inhibition and the pathogenesis of various diseases. Herein, we confirmed that norvaline (Nva) but not isoleucine or valine is the major thr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499588/ https://www.ncbi.nlm.nih.gov/pubmed/28575390 http://dx.doi.org/10.1093/nar/gkx487 |