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Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain

The editing function of aminoacyl-tRNA synthetases (aaRSs) is indispensible for formation of the correct aminoacyl-tRNAs. Editing deficiency may lead to growth inhibition and the pathogenesis of various diseases. Herein, we confirmed that norvaline (Nva) but not isoleucine or valine is the major thr...

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Detalles Bibliográficos
Autores principales:	Ji, Quan-Quan, Fang, Zhi-Peng, Ye, Qing, Chi, Cheng-Wu, Wang, En-Duo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499588/ https://www.ncbi.nlm.nih.gov/pubmed/28575390 http://dx.doi.org/10.1093/nar/gkx487

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