A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing

Although strong evidence supports the importance of their cooperative interactions, microRNA (miRNA)-binding sites are still largely investigated as functionally independent regulatory units. Here, a survey of alternative 3΄UTR isoforms implicates a non-canonical seedless site in cooperative miRNA-m...

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Detalles Bibliográficos
Autores principales: Flamand, Mathieu N., Gan, Hin Hark, Mayya, Vinay K., Gunsalus, Kristin C., Duchaine, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499589/
https://www.ncbi.nlm.nih.gov/pubmed/28482037
http://dx.doi.org/10.1093/nar/gkx340

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