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Replication studies of carboxymethylated DNA lesions in human cells

Metabolic activation of some N-nitroso compounds (NOCs), an important class of DNA damaging agents, can induce the carboxymethylation of nucleobases in DNA. Very little was previously known about how the carboxymethylated DNA lesions perturb DNA replication in human cells. Here, we investigated the...

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Detalles Bibliográficos
Autores principales:	Wu, Jun, Wang, Pengcheng, Li, Lin, Williams, Nicole L., Ji, Debin, Zahurancik, Walter J., You, Changjun, Wang, Jianshuang, Suo, Zucai, Wang, Yinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499590/ https://www.ncbi.nlm.nih.gov/pubmed/28531304 http://dx.doi.org/10.1093/nar/gkx442

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