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Statistical analysis of genetic interactions in Tn-Seq data

Tn-Seq is an experimental method for probing the functions of genes through construction of complex random transposon insertion libraries and quantification of each mutant's abundance using next-generation sequencing. An important emerging application of Tn-Seq is for identifying genetic intera...

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Detalles Bibliográficos
Autores principales: DeJesus, Michael A., Nambi, Subhalaxmi, Smith, Clare M., Baker, Richard E., Sassetti, Christopher M., Ioerger, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499643/
https://www.ncbi.nlm.nih.gov/pubmed/28334803
http://dx.doi.org/10.1093/nar/gkx128