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Probing the CMP‐Sialic Acid Donor Specificity of Two Human β‐d‐Galactoside Sialyltransferases (ST3Gal I and ST6Gal I) Selectively Acting on O‐ and N‐Glycosylproteins

Sialylation of glycoproteins and glycolipids is catalyzed by sialyltransferases in the Golgi of mammalian cells, whereby sialic acid residues are added at the nonreducing ends of oligosaccharides. Because sialylated glycans play critical roles in a number of human physio‐pathological processes, the...

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Detalles Bibliográficos
Autores principales: Noel, Maxence, Gilormini, Pierre‐André, Cogez, Virginie, Yamakawa, Nao, Vicogne, Dorothée, Lion, Cédric, Biot, Christophe, Guérardel, Yann, Harduin‐Lepers, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499661/
https://www.ncbi.nlm.nih.gov/pubmed/28395125
http://dx.doi.org/10.1002/cbic.201700024