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MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis

Histone H3K4me1/2 methyltransferases MLL3/MLL4 and H3K27 acetyltransferases CBP/p300 are major enhancer epigenomic writers. To understand how these epigenomic writers orchestrate enhancer landscapes in cell differentiation, we have profiled genomic binding of MLL4, CBP, lineage-determining transcrip...

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Detalles Bibliográficos
Autores principales:	Lai, Binbin, Lee, Ji-Eun, Jang, Younghoon, Wang, Lifeng, Peng, Weiqun, Ge, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499743/ https://www.ncbi.nlm.nih.gov/pubmed/28398509 http://dx.doi.org/10.1093/nar/gkx234

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