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Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation

The poly-A specific ribonuclease (PARN), initially characterized for its role in mRNA catabolism, supports the processing of different types of non-coding RNAs including telomerase RNA. Mutations in PARN are linked to dyskeratosis congenita and pulmonary fibrosis. Here, we show that PARN is part of...

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Detalles Bibliográficos
Autores principales: Montellese, Christian, Montel-Lehry, Nathalie, Henras, Anthony K., Kutay, Ulrike, Gleizes, Pierre-Emmanuel, O’Donohue, Marie-Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499762/
https://www.ncbi.nlm.nih.gov/pubmed/28402503
http://dx.doi.org/10.1093/nar/gkx253