Cargando…
Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation
The poly-A specific ribonuclease (PARN), initially characterized for its role in mRNA catabolism, supports the processing of different types of non-coding RNAs including telomerase RNA. Mutations in PARN are linked to dyskeratosis congenita and pulmonary fibrosis. Here, we show that PARN is part of...
Autores principales: | Montellese, Christian, Montel-Lehry, Nathalie, Henras, Anthony K., Kutay, Ulrike, Gleizes, Pierre-Emmanuel, O’Donohue, Marie-Françoise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499762/ https://www.ncbi.nlm.nih.gov/pubmed/28402503 http://dx.doi.org/10.1093/nar/gkx253 |
Ejemplares similares
-
Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
por: Preti, Milena, et al.
Publicado: (2013) -
Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals
por: Carron, Coralie, et al.
Publicado: (2011) -
Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing
por: Larburu, Natacha, et al.
Publicado: (2016) -
The final step of 40S ribosomal subunit maturation is controlled by a dual key lock
por: Plassart, Laura, et al.
Publicado: (2021) -
Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2
por: Zemp, Ivo, et al.
Publicado: (2009)