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Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence
Mycobacterium tuberculosis (MTb) is the causative agent of pulmonary tuberculosis (TB). MTb colonizes the human lung, often entering a non-replicating state before progressing to life-threatening active infections. Transcriptional reprogramming is essential for TB pathogenesis. In vitro, Cmr (a memb...
Autores principales: | Smith, Laura J., Bochkareva, Aleksandra, Rolfe, Matthew D., Hunt, Debbie M., Kahramanoglou, Christina, Braun, Yvonne, Rodgers, Angela, Blockley, Alix, Coade, Stephen, Lougheed, Kathryn E.A., Hafneh, Nor Azian, Glenn, Sarah M., Crack, Jason C., Le Brun, Nick E., Saldanha, José W., Makarov, Vadim, Nobeli, Irene, Arnvig, Kristine, Mukamolova, Galina V., Buxton, Roger S., Green, Jeffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499769/ https://www.ncbi.nlm.nih.gov/pubmed/28482027 http://dx.doi.org/10.1093/nar/gkx406 |
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