Optimization of RNA 3D structure prediction using evolutionary restraints of nucleotide–nucleotide interactions from direct coupling analysis

Direct coupling analysis of nucleotide coevolution provides a novel approach to identify which nucleotides in an RNA molecule are likely in direct contact, and this information obtained from sequence only can be used to predict RNA 3D structures with much improved accuracy. Here we present an effici...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Mao, Kangkun, Zhao, Yunjie, Zeng, Chen, Xiang, Jianjin, Zhang, Yi, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499770/
https://www.ncbi.nlm.nih.gov/pubmed/28482022
http://dx.doi.org/10.1093/nar/gkx386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499770/
https://www.ncbi.nlm.nih.gov/pubmed/28482022
http://dx.doi.org/10.1093/nar/gkx386

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