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Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study

Background: Growth hormone (GH) is known to affect insulin and glucose metabolism.  Blocking its effects in acromegalic patients improves diabetes and glucose metabolism. We aimed to determine the effect of pegvisomant, a GH receptor antagonist, on insulin resistance, endogenous glucose production (...

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Detalles Bibliográficos
Autores principales: Lee, Ada P., Mulligan, Kathleen, Schambelan, Morris, Murphy, Elizabeth J., Weiss, Ethan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499778/
https://www.ncbi.nlm.nih.gov/pubmed/28713554
http://dx.doi.org/10.12688/f1000research.11359.1

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