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Large-scale recoding of a bacterial genome by iterative recombineering of synthetic DNA

The ability to rewrite large stretches of genomic DNA enables the creation of new organisms with customized functions. However, few methods currently exist for accumulating such widespread genomic changes in a single organism. In this study, we demonstrate a rapid approach for rewriting bacterial ge...

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Detalles Bibliográficos
Autores principales:	Lau, Yu Heng, Stirling, Finn, Kuo, James, Karrenbelt, Michiel A. P., Chan, Yujia A., Riesselman, Adam, Horton, Connor A., Schäfer, Elena, Lips, David, Weinstock, Matthew T., Gibson, Daniel G., Way, Jeffrey C., Silver, Pamela A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499800/ https://www.ncbi.nlm.nih.gov/pubmed/28499033 http://dx.doi.org/10.1093/nar/gkx415

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