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Human DDX21 binds and unwinds RNA guanine quadruplexes

Guanine quadruplexes (G4s) are an important structure of nucleic acids (DNA and RNA) with roles in several cellular processes. RNA G4s require specialized unwinding enzymes, of which only two have been previously identified. We describe the results of a simple and specific mass spectrometry guided m...

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Detalles Bibliográficos
Autores principales:	McRae, Ewan K.S., Booy, Evan P., Moya-Torres, Aniel, Ezzati, Peyman, Stetefeld, Jörg, McKenna, Sean A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499804/ https://www.ncbi.nlm.nih.gov/pubmed/28472472 http://dx.doi.org/10.1093/nar/gkx380

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