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Krüppel-like factors compete for promoters and enhancers to fine-tune transcription

Krüppel-like factors (KLFs) are a family of 17 transcription factors characterized by a conserved DNA-binding domain of three zinc fingers and a variable N-terminal domain responsible for recruiting cofactors. KLFs have diverse functions in stem cell biology, embryo patterning, and tissue homoeostas...

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Detalles Bibliográficos
Autores principales: Ilsley, Melissa D., Gillinder, Kevin R., Magor, Graham W., Huang, Stephen, Bailey, Timothy L., Crossley, Merlin, Perkins, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499887/
https://www.ncbi.nlm.nih.gov/pubmed/28541545
http://dx.doi.org/10.1093/nar/gkx441