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Advances in phase plate cryo-EM imaging of DNA and nucleosomes
Contrast in electron cryo-microscopy (cryo-EM) is limited by the weak phase and radiation sensitive nature of biologic samples embedded in vitrified ice. We have recently shown that a new contrast enhancement technique utilizing the Volta phase plate can be combined with single particle analysis to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499919/ https://www.ncbi.nlm.nih.gov/pubmed/28340334 http://dx.doi.org/10.1080/19491034.2017.1287643 |