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Biomaterials: A potential pathway to healing chronic wounds?
Chronic dermal wounds are a devastating problem, which disproportionally affect individuals with conditions such as diabetes, paralysis, or simply old age. These wounds are extremely challenging to treat due to a heterogeneous combination of causative factors, creating a substantial burden on health...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500184/ https://www.ncbi.nlm.nih.gov/pubmed/28094868 http://dx.doi.org/10.1111/exd.13290 |
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author | Pop, Mara A. Almquist, Benjamin D. |
author_facet | Pop, Mara A. Almquist, Benjamin D. |
author_sort | Pop, Mara A. |
collection | PubMed |
description | Chronic dermal wounds are a devastating problem, which disproportionally affect individuals with conditions such as diabetes, paralysis, or simply old age. These wounds are extremely challenging to treat due to a heterogeneous combination of causative factors, creating a substantial burden on healthcare systems worldwide. Despite their large impact, there is currently a startling lack of options for effectively treating the underlying biological changes that occur within the wounds. Biomaterials possess an enticing ability to provide new comprehensive approaches to healing these devastating wounds; advanced wound dressings are now being developed that enable the ability to coordinate temporal delivery of multiple therapeutics, protect sensitive biologics from degradation, and provide supportive matrices that encourage the growth of tissue. This positions biomaterials as a potential “conductor” of wound repair, allowing them to simultaneously address numerous barriers to healing, and in turn providing a promising pathway to innovative new technologies for driving successful healing. |
format | Online Article Text |
id | pubmed-5500184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55001842017-09-01 Biomaterials: A potential pathway to healing chronic wounds? Pop, Mara A. Almquist, Benjamin D. Exp Dermatol Viewpoint Chronic dermal wounds are a devastating problem, which disproportionally affect individuals with conditions such as diabetes, paralysis, or simply old age. These wounds are extremely challenging to treat due to a heterogeneous combination of causative factors, creating a substantial burden on healthcare systems worldwide. Despite their large impact, there is currently a startling lack of options for effectively treating the underlying biological changes that occur within the wounds. Biomaterials possess an enticing ability to provide new comprehensive approaches to healing these devastating wounds; advanced wound dressings are now being developed that enable the ability to coordinate temporal delivery of multiple therapeutics, protect sensitive biologics from degradation, and provide supportive matrices that encourage the growth of tissue. This positions biomaterials as a potential “conductor” of wound repair, allowing them to simultaneously address numerous barriers to healing, and in turn providing a promising pathway to innovative new technologies for driving successful healing. John Wiley and Sons Inc. 2017-02-14 2017-09 /pmc/articles/PMC5500184/ /pubmed/28094868 http://dx.doi.org/10.1111/exd.13290 Text en © 2017 The Authors. Experimental Dermatology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Viewpoint Pop, Mara A. Almquist, Benjamin D. Biomaterials: A potential pathway to healing chronic wounds? |
title | Biomaterials: A potential pathway to healing chronic wounds? |
title_full | Biomaterials: A potential pathway to healing chronic wounds? |
title_fullStr | Biomaterials: A potential pathway to healing chronic wounds? |
title_full_unstemmed | Biomaterials: A potential pathway to healing chronic wounds? |
title_short | Biomaterials: A potential pathway to healing chronic wounds? |
title_sort | biomaterials: a potential pathway to healing chronic wounds? |
topic | Viewpoint |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500184/ https://www.ncbi.nlm.nih.gov/pubmed/28094868 http://dx.doi.org/10.1111/exd.13290 |
work_keys_str_mv | AT popmaraa biomaterialsapotentialpathwaytohealingchronicwounds AT almquistbenjamind biomaterialsapotentialpathwaytohealingchronicwounds |