Cargando…
Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells
Tyrosine kinase inhibitors (TKIs) are currently the first-line treatment for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. These patients receive platinum-based chemotherapy as the second-line treatment after they develop resistance to TKIs. Many...
Autores principales: | Lee, An-Fu, Chen, Man-Chin, Chen, Chao-Ju, Yang, Chih-Jen, Huang, Ming-Shyang, Liu, Yu-Peng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500319/ https://www.ncbi.nlm.nih.gov/pubmed/28683123 http://dx.doi.org/10.1371/journal.pone.0180383 |
Ejemplares similares
-
Role of the ABL tyrosine kinases in the epithelial–mesenchymal transition and the metastatic cascade
por: Luttman, Jillian Hattaway, et al.
Publicado: (2021) -
Proline-Rich Tyrosine Kinase 2 (Pyk2) Promotes Cell Motility of Hepatocellular Carcinoma through Induction of Epithelial to Mesenchymal Transition
por: Sun, Chris K., et al.
Publicado: (2011) -
SAT-335 Resistin Induces Epithelial to Mesenchymal Transition (EMT) in Breast Cancer Cells through Activation of AXL Tyrosine Kinase Receptor
por: Weber, Daniel, et al.
Publicado: (2019) -
Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase
por: Zhang, Nan-nan, et al.
Publicado: (2020) -
Inhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma
por: Ge, Yang, et al.
Publicado: (2022)