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Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes

Group A Streptococcus (GAS) is deleterious pathogenic bacteria whose interaction with blood vessels leads to life-threatening bacteremia. Although xenophagy, a special form of autophagy, eliminates invading GAS in epithelial cells, we found that GAS could survive and multiply in endothelial cells. E...

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Detalles Bibliográficos
Autores principales: Lu, Shiou-Ling, Kawabata, Tsuyoshi, Cheng, Yi-Lin, Omori, Hiroko, Hamasaki, Maho, Kusaba, Tatsuya, Iwamoto, Ryo, Arimoto, Hirokazu, Noda, Takeshi, Lin, Yee-Shin, Yoshimori, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500369/
https://www.ncbi.nlm.nih.gov/pubmed/28683091
http://dx.doi.org/10.1371/journal.ppat.1006444