Cargando…
Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes
Group A Streptococcus (GAS) is deleterious pathogenic bacteria whose interaction with blood vessels leads to life-threatening bacteremia. Although xenophagy, a special form of autophagy, eliminates invading GAS in epithelial cells, we found that GAS could survive and multiply in endothelial cells. E...
Autores principales: | Lu, Shiou-Ling, Kawabata, Tsuyoshi, Cheng, Yi-Lin, Omori, Hiroko, Hamasaki, Maho, Kusaba, Tatsuya, Iwamoto, Ryo, Arimoto, Hirokazu, Noda, Takeshi, Lin, Yee-Shin, Yoshimori, Tamotsu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500369/ https://www.ncbi.nlm.nih.gov/pubmed/28683091 http://dx.doi.org/10.1371/journal.ppat.1006444 |
Ejemplares similares
-
Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy
por: Cheng, Yi-Lin, et al.
Publicado: (2019) -
VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes
por: Lu, Shiou-Ling, et al.
Publicado: (2022) -
Erratum for Cheng et al., “Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy”
por: Cheng, Yi-Lin, et al.
Publicado: (2021) -
Monitoring and assessment of lysosomal membrane damage in cultured cells using the high-content imager
por: Tabata, Keisuke, et al.
Publicado: (2023) -
Autophagosome biogenesis and human health
por: Kawabata, Tsuyoshi, et al.
Publicado: (2020)