The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain

Pain is a severe and debilitating complication of metastatic bone cancer. Current analgesics do not provide sufficient pain relief for all patients, creating a great need for new treatment options. The Src kinase, a non-receptor protein tyrosine kinase, is implicated in processes involved in cancer-...

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Detalles Bibliográficos
Autores principales: Appel, Camilla Kristine, Gallego-Pedersen, Simone, Andersen, Line, Blancheflor Kristensen, Sophie, Ding, Ming, Falk, Sarah, Sayilekshmy, Manasi, Gabel-Jensen, Charlotte, Heegaard, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500481/
https://www.ncbi.nlm.nih.gov/pubmed/28684771
http://dx.doi.org/10.1038/s41598-017-05029-1

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