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Preparation of exenatide-loaded linear poly(ethylene glycol)-brush poly(l-lysine) block copolymer: potential implications on diabetic nephropathy
The poly(ethylene glycol)-b-brush poly(l-lysine) polymer (PEG-b-(PELG(50)-g-PLL(3))) was synthesized and evaluated as a nanocarrier for prolonging delivery of exenatide through the abdominal subcutaneous injection route. The isoelectric point of exenatide was 4.86, and exenatide could combine with P...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500490/ https://www.ncbi.nlm.nih.gov/pubmed/28721043 http://dx.doi.org/10.2147/IJN.S136646 |