Retinoic Acid affects Lung Adenocarcinoma growth by inducing differentiation via GATA6 activation and EGFR and Wnt inhibition

A fundamental task in cancer research aims at the identification of new pharmacological therapies that can affect tumor growth. Differentiation therapy might exploit this function not only for hematological diseases, such as acute promyelocytic leukemia (APML) but also for epithelial tumors, includi...

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Detalles Bibliográficos
Autores principales: Zito, Giovanni, Naselli, Flores, Saieva, Laura, Raimondo, Stefania, Calabrese, Giovanna, Guzzardo, Claudio, Forte, Stefano, Rolfo, Christian, Parenti, Rosalba, Alessandro, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500497/
https://www.ncbi.nlm.nih.gov/pubmed/28684780
http://dx.doi.org/10.1038/s41598-017-05047-z

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