Cargando…

Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis

Medialization laryngoplasty is the standard surgical treatment for unilateral vocal fold paralysis. This study presents a modified approach in which a thyroid cartilage graft is implanted in medialization laryngoplasty. 22 patients who underwent this approach were included in the study. The results...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Ming-Shao, Yang, Ming-Yu, Chang, Geng-He, Tsai, Yao-Te, Lin, Meng-Hung, Hsu, Cheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500551/
https://www.ncbi.nlm.nih.gov/pubmed/28684786
http://dx.doi.org/10.1038/s41598-017-05024-6
_version_ 1783248651195252736
author Tsai, Ming-Shao
Yang, Ming-Yu
Chang, Geng-He
Tsai, Yao-Te
Lin, Meng-Hung
Hsu, Cheng-Ming
author_facet Tsai, Ming-Shao
Yang, Ming-Yu
Chang, Geng-He
Tsai, Yao-Te
Lin, Meng-Hung
Hsu, Cheng-Ming
author_sort Tsai, Ming-Shao
collection PubMed
description Medialization laryngoplasty is the standard surgical treatment for unilateral vocal fold paralysis. This study presents a modified approach in which a thyroid cartilage graft is implanted in medialization laryngoplasty. 22 patients who underwent this approach were included in the study. The results revealed that glottal incompetence and vocal performance were markedly improved following surgery, and the follow-up period ranged from 6 to 74 months (mean, 21.4 months). Acoustic analysis revealed significant improvements in the maximum phonation time (from 3.51 to 7.89 seconds, p < 0.001), F0 (from 221.7 to 171.0 Hertz, p = 0.025), and jitter (from 7.68 to 3.19, p < 0.001). Perceptual assessment revealed a significant decrease in voice grading (from 2.59 to 1.41, p < 0.001), roughness (from 1.82 to 1.23, p = 0.004), and voice breathiness (from 2.55 to 1.23, p < 0.001). None of the patients exhibited severe wound infection, tissue rejection, or other complications attributed to the surgical procedure. In conclusion, autologous thyroid cartilage implantation in medialization laryngoplasty medializes the vocal cord, minimizes the glottal gap, and improves the voice of patients with vocal fold paralysis. This procedure is characterized by simplicity, safety, and acceptable results.
format Online
Article
Text
id pubmed-5500551
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-55005512017-07-10 Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis Tsai, Ming-Shao Yang, Ming-Yu Chang, Geng-He Tsai, Yao-Te Lin, Meng-Hung Hsu, Cheng-Ming Sci Rep Article Medialization laryngoplasty is the standard surgical treatment for unilateral vocal fold paralysis. This study presents a modified approach in which a thyroid cartilage graft is implanted in medialization laryngoplasty. 22 patients who underwent this approach were included in the study. The results revealed that glottal incompetence and vocal performance were markedly improved following surgery, and the follow-up period ranged from 6 to 74 months (mean, 21.4 months). Acoustic analysis revealed significant improvements in the maximum phonation time (from 3.51 to 7.89 seconds, p < 0.001), F0 (from 221.7 to 171.0 Hertz, p = 0.025), and jitter (from 7.68 to 3.19, p < 0.001). Perceptual assessment revealed a significant decrease in voice grading (from 2.59 to 1.41, p < 0.001), roughness (from 1.82 to 1.23, p = 0.004), and voice breathiness (from 2.55 to 1.23, p < 0.001). None of the patients exhibited severe wound infection, tissue rejection, or other complications attributed to the surgical procedure. In conclusion, autologous thyroid cartilage implantation in medialization laryngoplasty medializes the vocal cord, minimizes the glottal gap, and improves the voice of patients with vocal fold paralysis. This procedure is characterized by simplicity, safety, and acceptable results. Nature Publishing Group UK 2017-07-06 /pmc/articles/PMC5500551/ /pubmed/28684786 http://dx.doi.org/10.1038/s41598-017-05024-6 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tsai, Ming-Shao
Yang, Ming-Yu
Chang, Geng-He
Tsai, Yao-Te
Lin, Meng-Hung
Hsu, Cheng-Ming
Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title_full Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title_fullStr Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title_full_unstemmed Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title_short Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
title_sort autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500551/
https://www.ncbi.nlm.nih.gov/pubmed/28684786
http://dx.doi.org/10.1038/s41598-017-05024-6
work_keys_str_mv AT tsaimingshao autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis
AT yangmingyu autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis
AT changgenghe autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis
AT tsaiyaote autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis
AT linmenghung autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis
AT hsuchengming autologousthyroidcartilagegraftimplantationinmedializationlaryngoplastyamodifiedapproachfortreatingunilateralvocalfoldparalysis