HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

Aldosterone and the Mineralocorticoid Receptor (MR) control hydroelectrolytic homeostasis and alterations of mineralocorticoid signaling pathway are involved in the pathogenesis of numerous human diseases, justifying the need to decipher molecular events controlling MR expression level. Here, we sho...

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Detalles Bibliográficos
Autores principales: Lema, Ingrid, Amazit, Larbi, Lamribet, Khadija, Fagart, Jérôme, Blanchard, Anne, Lombès, Marc, Cherradi, Nadia, Viengchareun, Say
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500589/
https://www.ncbi.nlm.nih.gov/pubmed/28684740
http://dx.doi.org/10.1038/s41598-017-04838-8

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