Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells

The combination of solid phase peptide synthesis and endo-β-N-acetylglucosaminidase (ENGase) catalysed glycosylation is a powerful convergent synthetic method allowing access to glycopeptides bearing full-length N-glycan structures. Mannose-terminated N-glycan oligosaccharides, produced by either to...

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Detalles Bibliográficos
Autores principales: McIntosh, Julie D., Brimble, Margaret A., Brooks, Anna E. S., Dunbar, P. Rod, Kowalczyk, Renata, Tomabechi, Yusuke, Fairbanks, Antony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500846/
https://www.ncbi.nlm.nih.gov/pubmed/28717478
http://dx.doi.org/10.1039/c5sc00952a

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