Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis

Lipoproteins serve essential roles in the bacterial cell envelope. The posttranslational modification pathway leading to lipoprotein synthesis involves three enzymes. All are potential targets for the development of new antibiotics. Here we report the crystal structure of the last enzyme in the path...

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Detalles Bibliográficos
Autores principales: Wiktor, Maciej, Weichert, Dietmar, Howe, Nicole, Huang, Chia-Ying, Olieric, Vincent, Boland, Coilín, Bailey, Jonathan, Vogeley, Lutz, Stansfeld, Phillip J., Buddelmeijer, Nienke, Wang, Meitian, Caffrey, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500888/
https://www.ncbi.nlm.nih.gov/pubmed/28675161
http://dx.doi.org/10.1038/ncomms15952

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