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An inhibitor of ubiquitin conjugation and aggresome formation

Proteasome inhibitors have revolutionized the treatment of multiple myeloma, and validated the therapeutic potential of the ubiquitin proteasome system (UPS). It is believed that in part, proteasome inhibitors elicit their therapeutic effect by inhibiting the degradation of misfolded proteins, which...

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Detalles Bibliográficos
Autores principales:	An, Heeseon, Statsyuk, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500945/ https://www.ncbi.nlm.nih.gov/pubmed/28717502 http://dx.doi.org/10.1039/c5sc01351h

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