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An efficient system for homology-dependent targeted gene integration in medaka (Oryzias latipes)
BACKGROUND: The CRISPR/Cas system is a powerful genome editing tool that enables targeted genome modifications in various organisms. In medaka (Oryzias latipes), targeted mutagenesis with small insertions and deletions using this system have become a robust technique and are now widely used. However...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500998/ https://www.ncbi.nlm.nih.gov/pubmed/28694996 http://dx.doi.org/10.1186/s40851-017-0071-x |