Cargando…
Implementation of an open adoption research data management system for clinical studies
BACKGROUND: Research institutions need to manage multiple studies with individual data sets, processing rules and different permissions. So far, there is no standard technology that provides an easy to use environment to create databases and user interfaces for clinical trials or research studies. T...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501040/ https://www.ncbi.nlm.nih.gov/pubmed/28683771 http://dx.doi.org/10.1186/s13104-017-2566-0 |
_version_ | 1783248737777221632 |
---|---|
author | Müller, Jan Heiss, Kirsten Ingmar Oberhoffer, Renate |
author_facet | Müller, Jan Heiss, Kirsten Ingmar Oberhoffer, Renate |
author_sort | Müller, Jan |
collection | PubMed |
description | BACKGROUND: Research institutions need to manage multiple studies with individual data sets, processing rules and different permissions. So far, there is no standard technology that provides an easy to use environment to create databases and user interfaces for clinical trials or research studies. Therefore various software solutions are being used—from custom software, explicitly designed for a specific study, to cost intensive commercial Clinical Trial Management Systems (CTMS) up to very basic approaches with self-designed Microsoft(®) databases. FINDINGS: The technology applied to conduct those studies varies tremendously from study to study, making it difficult to evaluate data across various studies (meta-analysis) and keeping a defined level of quality in database design, data processing, displaying and exporting. Furthermore, the systems being used to collect study data are often operated redundantly to systems used in patient care. As a consequence the data collection in studies is inefficient and data quality may suffer from unsynchronized datasets, non-normalized database scenarios and manually executed data transfers. CONCLUSIONS: With OpenCampus Research we implemented an open adoption software (OAS) solution on an open source basis, which provides a standard environment for state-of-the-art research database management at low cost. |
format | Online Article Text |
id | pubmed-5501040 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-55010402017-07-10 Implementation of an open adoption research data management system for clinical studies Müller, Jan Heiss, Kirsten Ingmar Oberhoffer, Renate BMC Res Notes Technical Note BACKGROUND: Research institutions need to manage multiple studies with individual data sets, processing rules and different permissions. So far, there is no standard technology that provides an easy to use environment to create databases and user interfaces for clinical trials or research studies. Therefore various software solutions are being used—from custom software, explicitly designed for a specific study, to cost intensive commercial Clinical Trial Management Systems (CTMS) up to very basic approaches with self-designed Microsoft(®) databases. FINDINGS: The technology applied to conduct those studies varies tremendously from study to study, making it difficult to evaluate data across various studies (meta-analysis) and keeping a defined level of quality in database design, data processing, displaying and exporting. Furthermore, the systems being used to collect study data are often operated redundantly to systems used in patient care. As a consequence the data collection in studies is inefficient and data quality may suffer from unsynchronized datasets, non-normalized database scenarios and manually executed data transfers. CONCLUSIONS: With OpenCampus Research we implemented an open adoption software (OAS) solution on an open source basis, which provides a standard environment for state-of-the-art research database management at low cost. BioMed Central 2017-07-06 /pmc/articles/PMC5501040/ /pubmed/28683771 http://dx.doi.org/10.1186/s13104-017-2566-0 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Technical Note Müller, Jan Heiss, Kirsten Ingmar Oberhoffer, Renate Implementation of an open adoption research data management system for clinical studies |
title | Implementation of an open adoption research data management system for clinical studies |
title_full | Implementation of an open adoption research data management system for clinical studies |
title_fullStr | Implementation of an open adoption research data management system for clinical studies |
title_full_unstemmed | Implementation of an open adoption research data management system for clinical studies |
title_short | Implementation of an open adoption research data management system for clinical studies |
title_sort | implementation of an open adoption research data management system for clinical studies |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501040/ https://www.ncbi.nlm.nih.gov/pubmed/28683771 http://dx.doi.org/10.1186/s13104-017-2566-0 |
work_keys_str_mv | AT mullerjan implementationofanopenadoptionresearchdatamanagementsystemforclinicalstudies AT heisskirsteningmar implementationofanopenadoptionresearchdatamanagementsystemforclinicalstudies AT oberhofferrenate implementationofanopenadoptionresearchdatamanagementsystemforclinicalstudies |