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The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia

BACKGROUND: Diabetes mellitus is becoming a big public health challenge, particularly in developing countries like Ethiopia. It is a manageable disease if early screening and follow up is made. However, as studies in Ethiopia are limited and unorganized, determining the magnitude of prediabetes and...

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Autores principales: Worede, Abebaw, Alemu, Shitaye, Gelaw, Yalemzewod Assefa, Abebe, Molla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501367/
https://www.ncbi.nlm.nih.gov/pubmed/28683811
http://dx.doi.org/10.1186/s13104-017-2571-3
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author Worede, Abebaw
Alemu, Shitaye
Gelaw, Yalemzewod Assefa
Abebe, Molla
author_facet Worede, Abebaw
Alemu, Shitaye
Gelaw, Yalemzewod Assefa
Abebe, Molla
author_sort Worede, Abebaw
collection PubMed
description BACKGROUND: Diabetes mellitus is becoming a big public health challenge, particularly in developing countries like Ethiopia. It is a manageable disease if early screening and follow up is made. However, as studies in Ethiopia are limited and unorganized, determining the magnitude of prediabetes and diabetes and identifying associated risk factors is quite essential. METHODS: A community-based, cross-sectional study was conducted from February to April 2015 among adults (aged ≥20 years) in a rural Koladiba town. A multistage sampling technique was used to select a total of 392 study participants. Data were collected after a fully informed written consent was obtained from each participant. Demographic, behavioral, and clinical data were collected using a well-structured questionnaire. Multivariable logistic regression models were fitted to control the effect of confounders. Adjusted odds ratios (AOR) with their 95% confidence intervals (95% CI) were computed to measure associations. A p value of <0.05 was considered as statistically significant. RESULTS: The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus were 12% (95% CI 9–16) and 2.3% (95% CI 1.1–4), respectively, in Koladiba. Overweight (AOR: 4.257, 95% CI 1.345–13.476), obesity (AOR: 5.26, 95% CI 1.138–24.316), hypertriglyceridemia (AOR: 2.83, 95% CI 1.451–5.521), and systolic hypertension (AOR: 3.858, 95% CI 1.62–9.189) were found to be independently associated with impaired fasting glucose. Positive family history of diabetes also showed a marginal association with impaired fasting glucose (p = 0.057). Male sex (p = 0.012) and hypertriglyceridemia (p = 0.030) were associated with undiagnosed diabetes mellitus. CONCLUSIONS: The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus are found to be significant. Obesity, hypertriglyceridemia, and systolic hypertension are independently associated with impaired fasting glucose among adults. We recommend that the community be aware of healthy life style, early screening, and maintain continuous follow up.
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spelling pubmed-55013672017-07-10 The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia Worede, Abebaw Alemu, Shitaye Gelaw, Yalemzewod Assefa Abebe, Molla BMC Res Notes Research Article BACKGROUND: Diabetes mellitus is becoming a big public health challenge, particularly in developing countries like Ethiopia. It is a manageable disease if early screening and follow up is made. However, as studies in Ethiopia are limited and unorganized, determining the magnitude of prediabetes and diabetes and identifying associated risk factors is quite essential. METHODS: A community-based, cross-sectional study was conducted from February to April 2015 among adults (aged ≥20 years) in a rural Koladiba town. A multistage sampling technique was used to select a total of 392 study participants. Data were collected after a fully informed written consent was obtained from each participant. Demographic, behavioral, and clinical data were collected using a well-structured questionnaire. Multivariable logistic regression models were fitted to control the effect of confounders. Adjusted odds ratios (AOR) with their 95% confidence intervals (95% CI) were computed to measure associations. A p value of <0.05 was considered as statistically significant. RESULTS: The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus were 12% (95% CI 9–16) and 2.3% (95% CI 1.1–4), respectively, in Koladiba. Overweight (AOR: 4.257, 95% CI 1.345–13.476), obesity (AOR: 5.26, 95% CI 1.138–24.316), hypertriglyceridemia (AOR: 2.83, 95% CI 1.451–5.521), and systolic hypertension (AOR: 3.858, 95% CI 1.62–9.189) were found to be independently associated with impaired fasting glucose. Positive family history of diabetes also showed a marginal association with impaired fasting glucose (p = 0.057). Male sex (p = 0.012) and hypertriglyceridemia (p = 0.030) were associated with undiagnosed diabetes mellitus. CONCLUSIONS: The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus are found to be significant. Obesity, hypertriglyceridemia, and systolic hypertension are independently associated with impaired fasting glucose among adults. We recommend that the community be aware of healthy life style, early screening, and maintain continuous follow up. BioMed Central 2017-07-06 /pmc/articles/PMC5501367/ /pubmed/28683811 http://dx.doi.org/10.1186/s13104-017-2571-3 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Worede, Abebaw
Alemu, Shitaye
Gelaw, Yalemzewod Assefa
Abebe, Molla
The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title_full The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title_fullStr The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title_full_unstemmed The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title_short The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia
title_sort prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural koladiba town, northwest ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501367/
https://www.ncbi.nlm.nih.gov/pubmed/28683811
http://dx.doi.org/10.1186/s13104-017-2571-3
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