Genome-wide characterization of Mediator recruitment, function, and regulation

Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in t...

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Detalles Bibliográficos
Autores principales: Grünberg, Sebastian, Zentner, Gabriel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501378/
https://www.ncbi.nlm.nih.gov/pubmed/28301289
http://dx.doi.org/10.1080/21541264.2017.1291082
Descripción
Sumario:Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in the regulation of gene expression.

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