Genome-wide characterization of Mediator recruitment, function, and regulation

Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in t...

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Detalles Bibliográficos
Autores principales: Grünberg, Sebastian, Zentner, Gabriel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501378/
https://www.ncbi.nlm.nih.gov/pubmed/28301289
http://dx.doi.org/10.1080/21541264.2017.1291082
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author Grünberg, Sebastian
Zentner, Gabriel E.
author_facet Grünberg, Sebastian
Zentner, Gabriel E.
author_sort Grünberg, Sebastian
collection PubMed
description Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in the regulation of gene expression.
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spelling pubmed-55013782017-07-12 Genome-wide characterization of Mediator recruitment, function, and regulation Grünberg, Sebastian Zentner, Gabriel E. Transcription Point-of-View Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in the regulation of gene expression. Taylor & Francis 2017-02-08 /pmc/articles/PMC5501378/ /pubmed/28301289 http://dx.doi.org/10.1080/21541264.2017.1291082 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Point-of-View
Grünberg, Sebastian
Zentner, Gabriel E.
Genome-wide characterization of Mediator recruitment, function, and regulation
title Genome-wide characterization of Mediator recruitment, function, and regulation
title_full Genome-wide characterization of Mediator recruitment, function, and regulation
title_fullStr Genome-wide characterization of Mediator recruitment, function, and regulation
title_full_unstemmed Genome-wide characterization of Mediator recruitment, function, and regulation
title_short Genome-wide characterization of Mediator recruitment, function, and regulation
title_sort genome-wide characterization of mediator recruitment, function, and regulation
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501378/
https://www.ncbi.nlm.nih.gov/pubmed/28301289
http://dx.doi.org/10.1080/21541264.2017.1291082
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