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The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K(+)-dependent constitutively active and another K(+)-independent with essential allosteric activation
In a previous phylogenetic study of the family of pyruvate kinase EC (2.7.1.40), a cluster with Glu117 and another with Lys117 were found (numbered according to the rabbit muscle enzyme). The sequences with Glu117 have been found to be K(+)-dependent, whereas those with Lys117 were K(+)-independent....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501398/ https://www.ncbi.nlm.nih.gov/pubmed/28686591 http://dx.doi.org/10.1371/journal.pone.0178673 |