Cargando…

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy

BACKGROUND: Effective treatment of Mycobacterium tuberculosis (Mtb) infection requires at least 6 months of daily therapy with multiple orally administered antibiotics. Although this drug regimen is administered annually to millions worldwide, the impact of such intensive antimicrobial treatment on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Namasivayam, Sivaranjani, Maiga, Mamoudou, Yuan, Wuxing, Thovarai, Vishal, Costa, Diego L., Mittereder, Lara R., Wipperman, Matthew F., Glickman, Michael S., Dzutsev, Amiran, Trinchieri, Giorgio, Sher, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501520/ https://www.ncbi.nlm.nih.gov/pubmed/28683818 http://dx.doi.org/10.1186/s40168-017-0286-2

Ejemplares similares

Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques
por: Namasivayam, Sivaranjani, et al.
Publicado: (2019)

The Dysbiosis Triggered by First-Line Tuberculosis Antibiotics Fails to Reduce Their Bioavailability
por: Namasivayam, Sivaranjani, et al.
Publicado: (2023)

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques
por: Sui, Yongjun, et al.
Publicado: (2018)

Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed
por: Wipperman, Matthew F., et al.
Publicado: (2017)

The Microbiome and Tuberculosis: Early Evidence for Cross Talk
por: Namasivayam, Sivaranjani, et al.
Publicado: (2018)

Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes
por: Costa, Diego L., et al.
Publicado: (2016)

Enhancement of CD4(+) T Cell Function as a Strategy for Improving Antibiotic Therapy Efficacy in Tuberculosis: Does It Work?
por: Costa, Diego L., et al.
Publicado: (2021)

A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
por: Amaral, Eduardo P., et al.
Publicado: (2019)

Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression
por: Chen, Jichun, et al.
Publicado: (2020)

Heme oxygenase-1 inhibition promotes IFNγ and NOS2 mediated control of Mycobacterium tuberculosis infection
por: Costa, Diego L, et al.
Publicado: (2020)

Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance
por: Ajith, Ashwin, et al.
Publicado: (2023)

BCG mediated protection of the lung against experimental SARS-CoV-2 infection
por: Hilligan, Kerry L., et al.
Publicado: (2023)

Early transcriptome changes associated with western diet induced NASH in Ldlr(−/−) mice points to activation of hepatic macrophages and an acute phase response
por: Padiadpu, Jyothi, et al.
Publicado: (2023)

Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis
por: Chen, Keqiang, et al.
Publicado: (2021)

Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions
por: Newman, Nolan K., et al.
Publicado: (2023)

Nucleotide excision repair/transcription gene defects in the fetus and impaired TFIIH-mediated function in transcription in placenta leading to preeclampsia
por: Moslehi, Roxana, et al.
Publicado: (2014)

Regulatory Role of T Cells Producing both Interferon γ and Interleukin 10 in Persistent Infection
por: Trinchieri, Giorgio
Publicado: (2001)

Multi‐omic network analysis identified betacellulin as a novel target of omega‐3 fatty acid attenuation of western diet‐induced nonalcoholic steatohepatitis
por: Padiadpu, Jyothi, et al.
Publicado: (2023)

Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis
por: Bomfim, Caio C. B., et al.
Publicado: (2022)

Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia
por: Moslehi, Roxana, et al.
Publicado: (2013)

Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer
por: Moslehi, Roxana, et al.
Publicado: (2020)

Editorial: Host-Directed Therapies for Tuberculosis
por: Costa, Diego L., et al.
Publicado: (2021)

Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation
por: Cardone, Marco, et al.
Publicado: (2014)

FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis
por: Liang, Weiwei, et al.
Publicado: (2020)

Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota
por: Namasivayam, Sivaranjani, et al.
Publicado: (2020)

Dysbiosis Triggers ACF Development in Genetically Predisposed Subjects
por: De Santis, Stefania, et al.
Publicado: (2021)

Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options
por: Hrncir, Tomas
Publicado: (2022)

Aerococcus urinae and Globicatella sanguinis Persist in Polymicrobial Urethral Catheter Biofilms Examined in Longitudinal Profiles at the Proteomic Level
por: Yu, Yanbao, et al.
Publicado: (2019)

Microbiome and Asthma: Microbial Dysbiosis and the Origins, Phenotypes, Persistence, and Severity of Asthma
por: Valverde-Molina, José, et al.
Publicado: (2023)

Sugar Fructose Triggers Gut Dysbiosis and Metabolic Inflammation with Cardiac Arrhythmogenesis
por: Cheng, Wan-Li, et al.
Publicado: (2021)

Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes
por: Rodrigues, Richard R., et al.
Publicado: (2021)

Current tuberculosis diagnostic tools & role of urease breath test
por: Maiga, Mamoudou, et al.
Publicado: (2012)

Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice
por: Hatter, Jessica A., et al.
Publicado: (2018)

Lantibiotics Produced by Oral Inhabitants as a Trigger for Dysbiosis of Human Intestinal Microbiota
por: Yonezawa, Hideo, et al.
Publicado: (2021)

Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12(+) macrophages
por: Li, Zhipeng, et al.
Publicado: (2022)

Predicting cancer immunotherapy response from gut microbiomes using machine learning models
por: Liang, Hai, et al.
Publicado: (2022)

Interleukin-10 production by effector T cells: Th1 cells show self control
por: Trinchieri, Giorgio
Publicado: (2007)

Innate inflammation and cancer: Is it time for cancer prevention?
por: Trinchieri, Giorgio
Publicado: (2011)

Type I interferon: friend or foe?
por: Trinchieri, Giorgio
Publicado: (2010)

Critical role for CX(3)CR1(+) mononuclear phagocytes in intestinal homeostasis
por: Trinchieri, Giorgio
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0cqolr9ik3agkod3bms1af7g6e