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Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494
Several intracellular pathogens arrest the phagosome maturation in the host cells to avoid transport to lysosomes. In contrast, the Leishmania containing parasitophorous vacuole (PV) is shown to recruit lysosomal markers and thus Leishmania is postulated to be residing in the phagolysosomes in macro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501680/ https://www.ncbi.nlm.nih.gov/pubmed/28650977 http://dx.doi.org/10.1371/journal.ppat.1006459 |