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Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP
SARA and endofin are endosomal adaptor proteins that drive Smad phosphorylation by ligand-activated transforming growth factor β/bone morphogenetic protein (TGFβ/BMP) receptors. We show in this study that SARA and endofin also recruit the tumor supressor HD-PTP, a master regulator of endosomal sorti...
Autores principales: | Gahloth, Deepankar, Levy, Colin, Walker, Louise, Wunderley, Lydia, Mould, A. Paul, Taylor, Sandra, Woodman, Philip, Tabernero, Lydia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501724/ https://www.ncbi.nlm.nih.gov/pubmed/28602823 http://dx.doi.org/10.1016/j.str.2017.05.005 |
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