5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells

Relapse and metastasis of nasopharyngeal carcinoma (NPC) are presumably attributed to cancer stem cells (CSCs). In recent years, chimeric antigen receptor (CAR)-modified immune effector cells have been shown to have impressive antitumour efficacy. In this study, we aimed to identify appropriate tumo...

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Detalles Bibliográficos
Autores principales: Guo, Xueyang, Zheng, Hang, Luo, Weiren, Zhang, Qianbing, Liu, Jingxian, Yao, Kaitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501797/
https://www.ncbi.nlm.nih.gov/pubmed/28687750
http://dx.doi.org/10.1038/s41598-017-04756-9

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