Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source

We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux rela...

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Autores principales: Gradl, Regine, Dierolf, Martin, Hehn, Lorenz, Günther, Benedikt, Yildirim, Ali Önder, Gleich, Bernhard, Achterhold, Klaus, Pfeiffer, Franz, Morgan, Kaye Susannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501835/
https://www.ncbi.nlm.nih.gov/pubmed/28687726
http://dx.doi.org/10.1038/s41598-017-04739-w
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author Gradl, Regine
Dierolf, Martin
Hehn, Lorenz
Günther, Benedikt
Yildirim, Ali Önder
Gleich, Bernhard
Achterhold, Klaus
Pfeiffer, Franz
Morgan, Kaye Susannah
author_facet Gradl, Regine
Dierolf, Martin
Hehn, Lorenz
Günther, Benedikt
Yildirim, Ali Önder
Gleich, Bernhard
Achterhold, Klaus
Pfeiffer, Franz
Morgan, Kaye Susannah
author_sort Gradl, Regine
collection PubMed
description We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 10(10) ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures.
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spelling pubmed-55018352017-07-10 Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source Gradl, Regine Dierolf, Martin Hehn, Lorenz Günther, Benedikt Yildirim, Ali Önder Gleich, Bernhard Achterhold, Klaus Pfeiffer, Franz Morgan, Kaye Susannah Sci Rep Article We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 10(10) ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures. Nature Publishing Group UK 2017-07-07 /pmc/articles/PMC5501835/ /pubmed/28687726 http://dx.doi.org/10.1038/s41598-017-04739-w Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Gradl, Regine
Dierolf, Martin
Hehn, Lorenz
Günther, Benedikt
Yildirim, Ali Önder
Gleich, Bernhard
Achterhold, Klaus
Pfeiffer, Franz
Morgan, Kaye Susannah
Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_full Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_fullStr Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_full_unstemmed Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_short Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_sort propagation-based phase-contrast x-ray imaging at a compact light source
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501835/
https://www.ncbi.nlm.nih.gov/pubmed/28687726
http://dx.doi.org/10.1038/s41598-017-04739-w
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