Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis

Lamin B1, a key component of the nuclear lamina, plays an important role in brain development. Ablation of endogenous Lamin B1 (Lmnb1) in the mouse strongly impairs embryonic brain development and corticogenesis. However, the mechanisms underlying these neurodevelopmental effects are unknown. Here,...

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Detalles Bibliográficos
Autores principales: Mahajani, Sameehan, Giacomini, Caterina, Marinaro, Federica, De Pietri Tonelli, Davide, Contestabile, Andrea, Gasparini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501862/
https://www.ncbi.nlm.nih.gov/pubmed/28687747
http://dx.doi.org/10.1038/s41598-017-05078-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501862/
https://www.ncbi.nlm.nih.gov/pubmed/28687747
http://dx.doi.org/10.1038/s41598-017-05078-6

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