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Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis
Lamin B1, a key component of the nuclear lamina, plays an important role in brain development. Ablation of endogenous Lamin B1 (Lmnb1) in the mouse strongly impairs embryonic brain development and corticogenesis. However, the mechanisms underlying these neurodevelopmental effects are unknown. Here,...
Autores principales: | Mahajani, Sameehan, Giacomini, Caterina, Marinaro, Federica, De Pietri Tonelli, Davide, Contestabile, Andrea, Gasparini, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501862/ https://www.ncbi.nlm.nih.gov/pubmed/28687747 http://dx.doi.org/10.1038/s41598-017-05078-6 |
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