Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis

A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy was performed. As AML relapsed 7 mont...

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Autores principales: Ochi, Testuro, Katayama, Yuta, Okatani, Takeshi, Imanaka, Ryota, Kyo, Kohei, Itagaki, Mitsuhiro, Katsutani, Shinya, Iwato, Koji, Asaoku, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501889/
https://www.ncbi.nlm.nih.gov/pubmed/28725544
http://dx.doi.org/10.1016/j.mmcr.2017.07.002
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author Ochi, Testuro
Katayama, Yuta
Okatani, Takeshi
Imanaka, Ryota
Kyo, Kohei
Itagaki, Mitsuhiro
Katsutani, Shinya
Iwato, Koji
Asaoku, Hideki
author_facet Ochi, Testuro
Katayama, Yuta
Okatani, Takeshi
Imanaka, Ryota
Kyo, Kohei
Itagaki, Mitsuhiro
Katsutani, Shinya
Iwato, Koji
Asaoku, Hideki
author_sort Ochi, Testuro
collection PubMed
description A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy was performed. As AML relapsed 7 months after onset, she received haploidentical stem cell transplantation under administration of liposomal amphotericin B. Despite experiencing severe acute graft-versus-host disease, she remains alive with no relapse of either zygomycosis or AML.
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spelling pubmed-55018892017-07-19 Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis Ochi, Testuro Katayama, Yuta Okatani, Takeshi Imanaka, Ryota Kyo, Kohei Itagaki, Mitsuhiro Katsutani, Shinya Iwato, Koji Asaoku, Hideki Med Mycol Case Rep Case Report A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy was performed. As AML relapsed 7 months after onset, she received haploidentical stem cell transplantation under administration of liposomal amphotericin B. Despite experiencing severe acute graft-versus-host disease, she remains alive with no relapse of either zygomycosis or AML. Elsevier 2017-07-04 /pmc/articles/PMC5501889/ /pubmed/28725544 http://dx.doi.org/10.1016/j.mmcr.2017.07.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Ochi, Testuro
Katayama, Yuta
Okatani, Takeshi
Imanaka, Ryota
Kyo, Kohei
Itagaki, Mitsuhiro
Katsutani, Shinya
Iwato, Koji
Asaoku, Hideki
Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title_full Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title_fullStr Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title_full_unstemmed Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title_short Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis
title_sort successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin b after invasive pulmonary zygomycosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501889/
https://www.ncbi.nlm.nih.gov/pubmed/28725544
http://dx.doi.org/10.1016/j.mmcr.2017.07.002
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