Cargando…

Brain-derived neurotrophic factor propeptide inhibits proliferation and induces apoptosis in C6 glioma cells

There are several forms of brain-derived neurotrophic factor (BDNF), the precursor of BDNF, mature BDNF, and BDNF propeptide. They exert different effects through different transmembrane receptor signaling systems. Precursor of BDNF is enzymatically cleaved, either by intracellular or by extracellul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Bangkun, Qin, Jun, Nie, Ying, Li, Yong, Chen, Qianxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Cellular, Molecular and Developmental Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502118/ https://www.ncbi.nlm.nih.gov/pubmed/28640008 http://dx.doi.org/10.1097/WNR.0000000000000828

Ejemplares similares

Depression in Adolescence and Brain-Derived Neurotrophic Factor
por: Lee, Boyoung, et al.
Publicado: (2022)

Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells
por: Meng, Pan, et al.
Publicado: (2019)

Resveratrol protects early brain injury after subarachnoid hemorrhage by activating autophagy and inhibiting apoptosis mediated by the Akt/mTOR pathway
por: Guo, Dan, et al.
Publicado: (2018)

Function of brain-derived neurotrophic factor in the hypothalamus: Implications for depression pathology
por: Autry, Anita E.
Publicado: (2022)

Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases
por: Numakawa, Tadahiro, et al.
Publicado: (2023)

Ferrostatin-1 attenuates brain injury in animal model of subarachnoid hemorrhage via phospholipase A2 activity of PRDX6
por: Wang, Huiqing, et al.
Publicado: (2023)

Hippocampal Volume and Plasma Brain-Derived Neurotrophic Factor Levels in Patients With Depression and Healthy Controls
por: Fujii, Rintaro, et al.
Publicado: (2022)

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor
por: Harre, Jennifer, et al.
Publicado: (2021)

Brain-Derived Neurotrophic Factor Is an Important Therapeutic Factor in Mesenchymal Stem Cell Secretions for Treatment of Traumatic Peripheral Pelvic Injuries
por: Yuan, Xiaoyi, et al.
Publicado: (2022)

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor
por: Harre, Jennifer, et al.
Publicado: (2022)

miR-128-3p inhibits the inflammation by targeting MAPK6 in penicillin-induced astrocytes
por: Pang, Yuejiu, et al.
Publicado: (2022)

PCI-24781 down-regulates EZH2 expression and then promotes glioma apoptosis by suppressing the PIK3K/Akt/mTOR pathway
por: Zhang, Wei, et al.
Publicado: (2014)

The protective role of (−)-epigallocatechin-3-gallate in thrombin-induced neuronal cell apoptosis and JNK-MAPK activation
por: He, Qianqian, et al.
Publicado: (2015)

Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model
por: Fogarty, Matthew J., et al.
Publicado: (2022)

rTMS Regulates the Balance Between Proliferation and Apoptosis of Spinal Cord Derived Neural Stem/Progenitor Cells
por: Zhao, Chen-Guang, et al.
Publicado: (2020)

Development and validation of brain-derived neurotrophic factor measurement in human urine samples as a non-invasive effect biomarker
por: Olivas-Martinez, Alicia, et al.
Publicado: (2023)

Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway
por: Luo, Hongbo, et al.
Publicado: (2022)

Tannic acid inhibits electrogenic Na+/HCO3− co-transporter activity in embryonic neural stem cell-derived radial glial-like cells
por: Nordström, Tommy, et al.
Publicado: (2020)

NBTI attenuates neuroinflammation and apoptosis partly by ENT1/NLRP3/Bcl2 pathway after subarachnoid hemorrhage in rats
por: Chen, Xiaowei, et al.
Publicado: (2021)

Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling
por: Zhou, Yue, et al.
Publicado: (2021)

Dopamine D1 and Glutamate Receptors Co-operate With Brain-Derived Neurotrophic Factor (BDNF) and TrkB to Modulate ERK Signaling in Adult Striatal Slices
por: Morella, Ilaria, et al.
Publicado: (2020)

Building better brains: the pleiotropic function of neurotrophic factors in postnatal cerebellar development
por: Boxy, Pia, et al.
Publicado: (2023)

Ferroptosis involved in sevoflurane-aggravated young rats brain injury induced by liver transplantation
por: Yu, Xi, et al.
Publicado: (2022)

Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke
por: Gredal, Hanne, et al.
Publicado: (2017)

Melatonin prevented spatial deficits and increases in brain asymmetric dimethylarginine in young bile duct ligation rats
por: Hsu, Mei-Hsin, et al.
Publicado: (2018)

Memantine protects blood–brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser(1412) phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3 inflammasome activation
por: Chen, Xiaowei, et al.
Publicado: (2021)

The distinct roles of various neurotransmitters in modulating methamphetamine-induced conditioned place preference in relevant brain regions in mice
por: Su, Hongliang, et al.
Publicado: (2021)

Development and Verification of Glutamatergic Synapse-Associated Prognosis Signature for Lower-Grade Gliomas
por: Ye, Liguo, et al.
Publicado: (2021)

Glial Cell Line-Derived Neurotrophic Factor Family Ligands, Players at the Interface of Neuroinflammation and Neuroprotection: Focus Onto the Glia
por: Kotliarova, Anastasiia, et al.
Publicado: (2021)

Investigation of the effects of high cervical spinal cord electrical stimulation on improving neurological dysfunction and its potential mechanism in rats with traumatic brain injury
por: Zhao, Peng-Cheng, et al.
Publicado: (2022)

Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB-dependent inflammatory responses following experimental traumatic brain injury in rats
por: Zan, Jie, et al.
Publicado: (2018)

Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood–brain barrier: [(17)O]H(2)O JJVCPE MRI study
por: Huber, Vincent J., et al.
Publicado: (2018)

A new nitronyl nitroxide radical with salicylic acid framework attenuates blood–brain barrier disruption and oxidative stress in a rat model of middle cerebral artery occlusion
por: Chen, Lei, et al.
Publicado: (2022)

Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge
por: Yang, Changqing, et al.
Publicado: (2022)

Inhibition of miR-25 aggravates diabetic peripheral neuropathy
por: Zhang, Yanzhuo, et al.
Publicado: (2018)

Fluoxetine attenuates prepulse inhibition deficit induced by neonatal administration of MK-801 in mice
por: Yang, Luyin, et al.
Publicado: (2020)

Quercitrin improved cognitive impairment through inhibiting inflammation induced by microglia in Alzheimer’s disease mice
por: Wang, Lixin, et al.
Publicado: (2022)

Inhibition of inflammatory factor TNF-α by ferrostatin-1 in microglia regulates necroptosis of oligodendrocyte precursor cells
por: Chai, Zhi, et al.
Publicado: (2023)

Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway
por: Luo, Jun, et al.
Publicado: (2018)

Correlation of in vitro infiltration with glioma histological type in organotypic brain slices
por: Palfi, S, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_pm36ftb5nd7hk8r53s2g253vb2