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Post hoc analyses of East Asian patients from the randomized placebo-controlled PREVAIL trial of enzalutamide in patients with chemotherapy-naïve, metastatic castration-resistant prostate cancer
BACKGROUND: Enzalutamide is an androgen receptor (AR) inhibitor that acts on different steps in the AR signaling pathway. In PREVAIL, an international, phase III, double-blind, placebo-controlled trial, enzalutamide significantly reduced the risk of radiographic progression by 81% (hazard ratio [HR]...
Autores principales: | Kim, Choung Soo, Choi, Young Deuk, Lee, Sang Eun, Lee, Hyun Moo, Ueda, Takeshi, Yonese, Junji, Fukagai, Takashi, Chiong, Edmund, Lau, Weber, Abhyankar, Sarang, Theeuwes, Ad, Tombal, Bertrand, Beer, Tomasz M., Kimura, Go |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502144/ https://www.ncbi.nlm.nih.gov/pubmed/28682871 http://dx.doi.org/10.1097/MD.0000000000007223 |
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