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The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition

T lymphocytes are stimulated when they recognize short peptides bound to class I proteins of the major histocompatibility complex (MHC) protein, as peptide–MHC complexes. Due to the diversity in T-cell receptor (TCR) molecules together with both the peptides and MHC proteins they bind to, it has bee...

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Detalles Bibliográficos
Autores principales: Eccleston, R. Charlotte, Wan, Shunzhou, Dalchau, Neil, Coveney, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502259/
https://www.ncbi.nlm.nih.gov/pubmed/28740497
http://dx.doi.org/10.3389/fimmu.2017.00797