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Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease

Mitochondrial Ca(2+) uptake plays a pivotal role both in cell energy balance and in cell fate determination. Studies on the role of mitochondrial Ca(2+) signaling in pathophysiology have been favored by the identification of the genes encoding the mitochondrial calcium uniporter (MCU) and its regula...

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Detalles Bibliográficos
Autores principales: Mammucari, Cristina, Gherardi, Gaia, Rizzuto, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502327/
https://www.ncbi.nlm.nih.gov/pubmed/28740830
http://dx.doi.org/10.3389/fonc.2017.00139