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The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering
T lymphocytes are important mediators of adoptive immunity but the mechanism of T cell receptor (TCR) triggering remains uncertain. The interspatial distance between engaged T cells and antigen-presenting cells (APCs) is believed to be important for topological rearrangement of membrane tyrosine pho...
Autores principales: | Chen, Bing-Mae, Al-Aghbar, Mohammad Ameen, Lee, Chien-Hsin, Chang, Tien-Ching, Su, Yu-Cheng, Li, Ya-Chen, Chang, Shih-En, Chen, Chin-Chuan, Chung, Tsai-Hua, Liao, Yuan-Chun, Lee, Chau-Hwang, Roffler, Steve R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502409/ https://www.ncbi.nlm.nih.gov/pubmed/28740495 http://dx.doi.org/10.3389/fimmu.2017.00793 |
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